منابع مشابه
Combinatorial effects of odorants on mouse behavior.
The mechanisms by which odors induce instinctive behaviors are largely unknown. Odor detection in the mouse nose is mediated by >1, 000 different odorant receptors (ORs) and trace amine-associated receptors (TAARs). Odor perceptions are encoded combinatorially by ORs and can be altered by slight changes in the combination of activated receptors. However, the stereotyped nature of instinctive od...
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A single nucleotide polymorphism (SNP) in the human mu-opioid receptor gene (OPRM1 A118G) has been widely studied for its association in a variety of drug addiction and pain sensitivity phenotypes; however, the extent of these adaptations and the mechanisms underlying these associations remain elusive. To clarify the functional mechanisms linking the OPRM1 A118G SNP to addiction and analgesia p...
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From a network medicine perspective, diseases are caused by perturbations in the dynamics of multiple interacting genes a disease module. A drug that is a suitable candidate for re-purposing, should affect perturbed disease modules other than the one for which it was designed. In other words, it must act on various disease modules. A systematic analysis of re purposing suitability requires deep...
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Objective: Silybum marianum has been used for centuries in herbal medicine for treatment of liver diseases. Currently, there is no data available on the possible effects of silymarin on fetal development. This study aimed to investigate the teratogenic effect of silymarin on BALB/c mice fetuses. Materials and Methods: A total of 40 pregnant mice were divided into 4 groups of 10 mice each. Three...
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Permethrin and Cypermethrin are synthetic pyrethroids, belonging to a group of insecticides with low mammalian toxicity and high insecticidal activity. The present study evaluated sub-acute toxicity of dermally administrated permethrin and cypermethrin in mice. Behavioral examination included assessments of lethality, weight gain, grooming, analgesymetry, anxiety, grasping, motor activity, and ...
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ژورنال
عنوان ژورنال: Psychonomic Science
سال: 1969
ISSN: 0033-3131
DOI: 10.3758/bf03331896